Effect of gastric acid resistant coating of fish oil capsules on intestinal uptake of eicosapentaenoic acid and docosahexaenoic acid

verfasst von

Inga Schneider, Jan Philipp Schuchardt, Henrike Meyer, Andreas Hahn

Abstract

Fish oil capsules with gastric acid resistant coatings have been shown to lower undesirable side effects. We compared the eicosapentaenoic acid (EPA). +. docosahexaenoic acid (DHA) uptake from uncoated and coated fish oil capsules. In a double-blinded crossover trial 12 healthy young men (mean age 31. years) were randomized to 1680. mg EPA. +. DHA as triacylglycerols in uncoated or coated fish oil capsules. Fatty acid levels were analyzed in plasma phospholipids at baseline and 2, 4, 6, 8, 24, 48 and 72. h after capsule ingestion. Statistical group comparisons on the basis of area under the curve values revealed no significant differences for EPA, DHA and total n-3 fatty acid levels between the different capsule formulations. In conclusion, this nutrikinetic study indicates that coating of fish oil capsules with a gastric acid resistant layer has no influence on the bioavailability of EPA. +. DHA.

Organisationseinheit(en)

Institut für Lebensmittelwissenschaft und Humanernährung
Abteilung Ernährungsphysiologie und Humanernährung

Typ

Artikel

Journal

Journal of functional foods

Band

3

Seiten

129-133

Anzahl der Seiten

5

ISSN

1756-4646

Publikationsdatum

04.2011

Publikationsstatus

Veröffentlicht

Peer-reviewed

Ja

ASJC Scopus Sachgebiete

Lebensmittelwissenschaften, Medizin (sonstige), Ernährung und Diätetik

Elektronische Version(en)

https://doi.org/10.1016/j.jff.2011.03.001 (Zugang: Unbekannt)