Influence of long-chain polyunsaturated fatty acids (LC-PUFAs) on cognitive and visual development

verfasst von
J. P. Schuchardt, A. Hahn
Abstract

Long-chain polyunsaturated fatty acids (LC-PUFAs), particularly docosahexaenoic acid (DHA) and arachidonic acid (AA), play a central role in infancy for normal brain development. They are involved in numerous neuronal processes, ranging from effects on membrane fluidity, signal transduction, neurotransmission to gene expression regulation. Since observational studies have indicated that the visual and cognitive performance of breastfed infants is advantaged compared to formula-fed infants, numerous randomized controlled studies have studied whether infant formulas supplemented with DHA or both DHA and AA would enhance visual and cognitive development of both term and preterm infants. This chapter gives an overview on the significance of LC-PUFAs in neurodevelopment, with a special focus on the findings from these studies.

Organisationseinheit(en)
Institut für Lebensmittelwissenschaft und Humanernährung
Abteilung Ernährungsphysiologie und Humanernährung
Typ
Beitrag in Buch/Sammelwerk
Seiten
32-78
Anzahl der Seiten
47
Publikationsdatum
07.2011
Publikationsstatus
Veröffentlicht
Peer-reviewed
Ja
ASJC Scopus Sachgebiete
Allgemeine Agrar- und Biowissenschaften, Allgemeine Biochemie, Genetik und Molekularbiologie, Allgemeine Medizin
Elektronische Version(en)
https://doi.org/10.1533/9780857092922.1.32 (Zugang: Unbekannt)