Promising bioactive properties of quercetin for potential food applications and health benefits

A review

authored by

Irtiqa Shabir, Vinay Kumar Pandey, Rafeeya Shams, Aamir Hussain Dar, Kshirod Kumar Dash, Shafat Ahmad Khan, Iqra Bashir, G. Jeevarathinam, Alexandru Vasile Rusu, Tuba Esatbeyoglu, R. Pandiselvam

Abstract

Naturally occurring phytochemicals with promising biological properties are quercetin and its derivatives. Quercetin has been thoroughly studied for its antidiabetic, antibacterial, anti-inflammatory, anti-Alzheimer's, anti-arthritic, antioxidant, cardiovascular, and wound-healing properties. Anticancer activity of quercetin against cancer cell lines has also recently been revealed. The majority of the Western diet contains quercetin and its derivatives, therefore consuming them as part of a meal or as a food supplement may be sufficient for people to take advantage of their preventive effects. Bioavailability-based drug-delivery systems of quercetin have been heavily studied. Fruits, seeds, vegetables, bracken fern, coffee, tea, and other plants all contain quercetin, as do natural colors. One naturally occurring antioxidant is quercetin, whose anticancer effects have been discussed in detail. It has several properties that could make it an effective anti-cancer agent. Numerous researches have shown that quercetin plays a substantial part in the suppression of cancer cells in the breast, colon, prostate, ovary, endometrial, and lung tumors. The current study includes a concise explanation of quercetin's action mechanism and potential health applications.

Organisation(s)

Institute of Food Science and Human Nutrition
Molecular Food Chemistry and Food Development

External Organisation(s)

Islamic University of Science and Technology (IUST)
Integral University
Axis Institute of Higher Education (AIHE)
Lovely Professional University (LPU)
Ghani Khan Choudhury Institute of Engineering and Technology (GKCIET)
Sher-e-Kashmir University of Agricultural Sciences and Technology of Kashmir
Hindusthan College of Engineering and Technology (HiCET)
University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca (USAMVCN)
ICAR - Central Plantation Crops Research Institute (CPCRI)

Type

Review article

Journal

Frontiers in Nutrition

Volume

9

Publication date

30.11.2022

Publication status

Published

Peer reviewed

Yes

ASJC Scopus subject areas

Food Science, Endocrinology, Diabetes and Metabolism, Nutrition and Dietetics

Sustainable Development Goals

SDG 3 - Good Health and Well-being

Electronic version(s)

https://doi.org/10.3389/fnut.2022.999752 (Access: Open)